Grey Horse Melanomas

eMail From Suzie H

On June 26, 2008, Suzie H. wrote:

Grey horse melanomas question:

my grey 23 year old has been on cimetidine for 5 years for treatment of melanomas. April 7 2008 He developed a high fever and pain in his groin area that lead to inflammation of his sheath. Was treated with banamine and antibiotics for 5 days and the swelling reduced. Once off of these, the swelling returned. This cycle of dependency on meds to keep the swelling at bay lead to an ultrasound and biopsy. The ultrasound did not show any melanoma in the area and the biopsy did not culture out to be any infection. I thought there must be a melanoma up high that was causing the tissue around it to swell.... we put him on steroid dexamethazone and the entire situation cleared within two days. But, as soon as he was off that, it returned with swelling . We changed to prednizone because it is safer and he has been on pred and antibiotics for 2 weeks. The symptoms changed. This time the swelling reduced, but the area was not soft anymore, but instead hardened up inside to the right of where the sheath joins the abdomen like the swelling had crystallized. We did a little biopsy and right away the fluid showed up in the syringe as black - melanoma. In going over the history.... I am wondering if in March when he was in a pasture with a year old foal, if when this foul I'm told "pounced on him" when my grey was mid roll - landing right on his abdomen.... I'm wondering, with your experience with melanomas if a melanoma can indeed rupture from impact and that it is draining? If this could be the case, then what happens to that drained off bit if it is all internal? Does the body absorb it? Does it grow anew in that new location? We doubled up on the prednizone to the max level that is still entirely safe and are continuing with the antibiotics twice a day as well. I discontinued cimetidine because I didn't want to add too many things to the cocktail but am continuing and the glucosamine and msm and ha that he has always had. To me, this April medical condition development must have been caused by trauma, as he has lived so long with these melanomas in complete comfort.

So my question is, in your experience, do you think this could be a ruptured melanoma that is draining. And if so, will it be absorbed? Does it mean that it was destroyed where it had been way up high in the abdomen where no one knew it was located?

Do you have any clues about whether internal melanomas can rupture and drain?

Thanks for your time.


On Jun 26, 2008, at 3:07 PM, Sue Crane wrote:

Hello Suzie.

I don't have an educated answer to your question, but I would hypothesize that it would be quite possible for an internal melanoma to rupture. What happens to the toxins, I don't really know. However, when my mare had a ruptured melanoma on her anus, I loaded her up with Bio-Sponge, which is supposed to help remove toxins from the system. Probably an herbal, homeopathic blood and liver cleanse would be beneficial, too, especially considering all the mess your horse has been taking.

I would try to contact your nearest veterinary hospital to see if there is someone on staff who would be willing to answer your questions.

Best of luck, and please keep me posted on your progress.


On Jun 26, 2008, at 5:25 PM, Suzie H. wrote:

Thanks Sue,

the vet was out here to do the biopsy on tuesday so she knows exactly what is going on.... but I haven't heard back about the theory of an internal rupture and then what happens to the ruptured material.... yet. She is excellent so I'm sure she will find out if she doesn't know. Other than being uncomfortable because it is the size of a lacrosse ball and hardness of one too.... his spirits and appetite are good and he actually still has a ton of energy. This is a horse that one vet two months ago gave only days to live because he misdiagnosed in a rectal exam some of the fluid build up for a beach ball sized tumor! I insisted on the steroid which he said wouldn't make one difference one way or another - which was the very thing that reduced the liquid all together. I left that vet and found this other one who is a lameness expert who performed the same rectal exam and found no such thing like a beach ball in there.... There are little ones up and around in there but more like a rubber jax ball size and that is what I believe ruptured....

I may add in the cimetidine again just to keep the growth at bay even though this current vet says there isn't any evidence that shows it does in fact reduce growth... while horses are on it the melanomas do continue to grow.... she said, so it's just hard to tell if they grow at a lesser rate or not...

Thanks for all your help. My son made a video of Matt only three days after he couldn't walk, was lethargic, no appetite and had swelling the size of a cows udder all around his sheath and was given the death sentence by that one vet..... saying there was nothing we could do but put him down, giving him three or four days to live. This video shows how wonderful those steroids ended up being really..... glad to have ditched that horrid vet. I will attach it.... we had all been in tears over thinking we would loose him,,,, when the steroids cleared everything up initially, we felt we had saved his life. Now, a month later, I wonder what the heck is going on in there with the changes maybe a ruptured melanoma, so we will monitor and see.... enjoy the video. He and my big warmblood are best buddies. I really hope he lives for years and years and gets over this blip. I loved your website photos. thanks for your help.

eMail From Caroline B

On June 25, 2008, Caroline B. wrote:

Just wanted to say thank you for putting info on your website about your dealings with melanomas. My 9 year old Connemara x TB has a large one on his throat (pic attached), I had him on Nubulas Cure last year but the vet told me not to waste my money so I took him off it, since then he has nodules on the other side of his throat where new melanomas are appearing so I may well put him back on Nubulas Cure i think.
Do you have any other tips for me? I am worried sick about him, altho his are large, they arent interfering with his eating ........ yet!!

many thanks for your time.

Hello Caroline.
> I know very well the heartbreak of dealing with melanomas. I would definitely put your horse back on Nublada's cure ASAP. It is expensive, but I found it effective, and it's well worth it. How long did you have him on Nublada's Cure last time? I found it took 30-90 days to see any effect. I also combined both Nublada's Cure and Cimetidine therapy. I can't say which was more effective, but I was pleased with the results, and felt it gave me an edge I wouldn't have with a single product.
> You may also want to do a regular herbal liver cleanse, just to help purge the body of toxins.
> Katie's melanomas have stabilized. I had her on Nublada's Cure and Cimetidine for a year, and she's been off now for about 6 months. I monitor her melanomas daily, and if I notice any new growth at all, I will put her back on the regimen.
> I'm sure you know that, because of the location of your horse's melanoma, it could very well impede his ability to eat. For this reason, it is imperative that you know the rate of growth. To determine whether, and how much, it is growing and/or shrinking, take a thin sheet of drawing or tracing paper and place it against his throat. With a pencil, softly trace over the protruding area. Use this as a guideline, measuring at least once a week.
> You may also want to limit chances of choke by feeding less irritating feed and forage. Your vet should be able to guide you on how to proceed. Perhaps a senior feed and chopped or forage hay?
> Although veterinarians do not recommend removing melanomas because of the chance that they may spread, any melanoma that impedes a bodily function must be treated surgically if it becomes life-threatening. There is no definitive research that has proven that they do spread when surgically removed properly, so I would personally take that risk.
> Keep in mind that a melanoma in a horse is not like that in a human. It is not, in itself, a death sentence. Many horses live well into their thirties with multiple melanomas. The danger occurs only if the melanoma is in a restrictive location.
> I wish you and your horse the best of luck. Please feel free to contact me anytime.
> Sue Crane

On Jun 26, 2008, at 6:27 AM, Caroline B. wrote:

Hi Sue

Thank you very much for the reply, I do appreciate all your advice, I will put him back on Nublada's Cure and continue to monitor its growth. Melanomas are such a worry - I hate them, but I'm taking a positive approach to it and not thinking the worst all the time, like I used too.

Thanks again for your help, I will let you know how we get on xxxxx